What is 2-Fluoro-2-oxo PCE

2-Fluoro-2-oxo PCE (hydrochloride) is a novel compound belonging to the arylcyclohexylamine class, which includes various dissociative anesthetics such as ketamine and phencyclidine. Its chemical structure features a cyclohexane ring with a fluorinated phenyl group, making it an analogue of ketamine where a chlorine atom is replaced by a fluorine atom. 2-Fluoro-2-oxo PCE Price

The full IUPAC name is 2-fluoro-2-oxo-N-ethyl-cyclohexanamine hydrochloride, with the molecular formula $C_{14} H_{19} ClFNO$ and a molar mass of approximately 271.76 g/mol.

Technical Information: 2-Fluoro-2-oxo PCE Price

Formal Name: 2-(ethylamino)-2-(2-fluorophenyl)-cyclohexanone, monohydrochloride
Molecular Formula: C₁₄H₁₈FNO • HCl
Formula Weight: 271.8
Purity: ≥98%
Formulation: A solid
SMILES: O=C1CCCCC1(NCC)C2=CC=CC=C2F.Cl
InChi Code: InChI=1S/C14H18FNO.ClH/c1-2-16-14(10-6-5-9-13(14)17)11-7-3-4-8-12(11)15;/h3-4,7-8,16H,2,5-6,9-10H2,1H3;1H
InChi Key: CAQVRTRJSIFTRP-UHFFFAOYSA-N

Shipping & Storage Information

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Stability : ≥ 5 years

Synthesis Methods

The synthesis of 2-fluoro-2-oxo PCE can be summarized in the following steps:

Reaction of 2-Fluorobenzonitrile with Grignard Reagent: This forms an intermediate compound.
Bromination: The intermediate undergoes bromination to yield α-bromocyclopentyl-(2-fluorophenyl)-ketone.
Reaction with Methylamine: Conducted at low temperatures to produce α-hydroxycyclopentyl-(2-fluorophenyl)-N-methylamine.
Thermal Rearrangement: Converts the five-membered ring structure into the cyclohexylketone form.
Formation of Hydrochloride Salt: Hydrochloric acid is added to create the hydrochloride salt for improved solubility .